Dr. LEE Dong-Yup

Assistant Professor

(Principal Investigator since Aug 2005)

Research Scientist, BTI

(Joint appointment since Aug 2005)

  • PhD (2004) & MSc (2000) in Chem. & Biomolecular Eng. KAIST, Korea
  • BSc in Chemical Engineering (1998) Yonsei Univ., Korea

Email: cheldnus.edu.sg
Tel: (65) 6516 6907


  • Computational Analysis and Engineering of Biological Systems
  • Bioinformatics Analysis of Omics Data
  • Bioinformatics Platform and Tool Development


Lakshmanan, M., S. -H. Lim, B. Mohanty, J. K. Kim, S. -H. Ha, and D.-Y. Lee. 2015. Unraveling the light-specific metabolic and regulatory signatures of rice through combined in silico modeling and multi-omics analysis. Plant Physiol., accepted.

Mohanty, B., A. Kitazumi, C. Y. M. Cheung, M. Lakshmanan, B. G. de los Reyes, I. -C. Jang, and D.-Y. Lee. 2015. Identification of candidate network hubs involved in metabolic adjustments of rice under drought stress by integrating transcriptome data and genome-scale metabolic network. Plant Sci. (Special Issue), accepted.

Kim, M., J. S. Yi, M. Lakshmanan, D.-Y. Lee and B.-G. Kim. 2015. Transcriptomics-based strain optimization tool for designing secondary metabolite overproducing strains of Streptomyces coelicolor. Biotechnol. Bioeng., accepted.

Lakshmanan, M., T. Y. Kim, B. K. S. Chung, S. Y. Lee and D.-Y. Lee. 2015. Flux-sum analysis identifies metabolite targets for strain improvement. BMC Syst. Biol., accepted.

Yeo, H. C., B. K.-S. Chung, W. Chong, J. X. Chin, K. S. Ang, M. Lakshmanan, Y. S. Ho and D.-Y. Lee. 2015. A genetic algorithm-based approach for pre-processing metabolomics and lipidomics LC-MS data. Metabolomics, accepted.

Liu, C., J. X. Chin, and D.-Y. Lee. 2015. SynLinker: an integrated system for designing linkers and synthetic fusion proteins. Bioinformatics, in press.

Lakshmanan, M., K. Yu, L. Koduru and D.-Y. Lee. 2015. In silico model-driven cofactor engineering strategies for improving the overall NADP(H) bioavailability in microbial cell factories. J. Ind. Microbiol. Biotechnol., in press.

Kwok, J. J. M. and D.-Y. Lee. 2015. Coopetitive supply chain relationship model: application to the smartphone manufacturing network. PLoS ONE, 10(7): e0132844.

Chen, B., D.-Y. Lee and M. W. Chang. 2015. Combinatorial metabolic engineering of Saccharomyces cerevisiae for terminal 2 alkene production. Metab. Eng., 31: 53-61.

Yu, N., L. T. J. Dieu, S. Harvey and D.-Y. Lee. 2015. Optimization of process configuration and strain selection for microalgae-based biodiesel production. Bioresour. Technol., 193: 25-34.

Pek, H. B., M. Klement, K. S. Ang, B. K. S. Chung, D. S.-W. Ow and D.-Y. Lee. 2015. Exploring codon context bias for designing a synthetic thermostable invertase gene in Escherichia coli. Enzyme Microb. Technol., 75-76: 57-63.

Klement, M., C. Liu, B. L. W. Loo, A. B.-H. Choo, D. S.-W. Ow and D.-Y. Lee. 2015. Effect of linker flexibility and length on the functionality of a cytotoxic engineered antibody fragment. J. Biotechnol., 199: 90-97.

de los Reyes, B. G., B. Mohanty, S.-J. Yun, M.-R. Park, and D.-Y. Lee. 2015. Upstream regulatory architecture of rice genes: Summarizing the baseline towards genus-wide comparative analysis of regulatory networks and allele mining. Rice, 8: 14. [Highly accessed].

Vishwanathan, N., A. Yongky, K. C. Johnson, H.-Y. Fu, N. M. Jacob, H. Le, F. N. K. Yusufi, D.-Y. Lee and W.-S. Hu. 2015. Global insights into the Chinese hamster and CHO cell transcriptomes. Biotechnol. Bioeng., 112(5): 965-976. [Spotlighted article]

Yu, K., C. Liu, B.-G Kim and D.-Y. Lee. 2015. Synthetic fusion protein design and applications. Biotechnol. Adv., 33: 155-164.

Lee, D.-Y. and K. Yu. 2014. Synthetic biology in Singapore. Asia Pacific Biotech News, 18(5): 35-38.

Lakshmanan, M., B. Mohanty, S.-H. Lim, S.-H. Ha, and D.-Y. Lee. 2014. Metabolic and transcriptional regulatory mechanisms underlying the anoxic adaptation of rice coleoptile. AoB PLANTS, 6: plu026.

Loh, W. P., B. Loo, L. Zhou, P. Zhang, D.-Y. Lee, Y. Yang, K. P. Lam. 2014. Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells. Biotechnol. J., 9(9): 1140-1151.

Lee, N.-R., M. Lakshmanan, S. Aggarwal, J.-W. Song, I. A. Karimi, D.-Y. Lee and J.-B. Park. 2014. Genome-scale metabolic network reconstruction and in silico flux analysis of the thermophilic bacterium Thermus thermophilus B27. Microb. Cell Fact., 13: 61.

Chin, J. X., B. K.-S. Chung and D.-Y. Lee. 2014. Codon Optimization On-Line (COOL): a web-based multi-objective optimization platform for synthetic gene design. Bioinformatics, 30(15): 2210-2212.

Park, S.-J., H. C. Yeo, N.-Y. Kang, H. Kim, J. Lin, H.-H. Ha, M. Vendrell, J.-S. Lee, Y. Chandran, D.-Y. Lee, S.-W. Yun and Y.-T. Chang. 2014. Mechanistic elements and critical factors of cellular reprogramming revealed by stepwise global gene expression analyses. Stem Cell Res., 12(3): 730-741.

Courtes, F. C., C. Gu, N. S. C. Wong, P. C. Dedon, M. G. S. Yap and D.-Y. Lee. 2014. 28S rRNA is inducibly pseudouridylated by the mTOR pathway in CHO cell cultures. J. Biotechnol., 174: 16-21.

Courtes, F. C., L. Vardy, N. S. C. Wong, M. Bardor, M. G. S. Yap and D.-Y. Lee. 2014. Understanding translational control mechanisms of the mTOR pathway in CHO cells by polysome profiling. New Biotechnol., 31(5): 514-523.

Lakshmanan, M., G. Koh, B. K. S. Chung and D.-Y. Lee. 2014. Software applications for flux balance analysis. Brief. Bioinform., 15(1): 108-122.

Lakshmanan, M., B. K.-S. Chung, C. Liu, S.-W. Kim and D.-Y. Lee. 2013. Cofactor modification analysis: a computational framework to identify cofactor specificity engineering targets for strain improvement. J. Bioinform. Comput. Biol., 11(6): 1343006.

Lakshmanan, M., B. Mohanty and D.-Y. Lee. 2013. Identifying essential genes/reactions of the rice photorespiration by in silico model-based analysis. Rice, 6: 20.

Chung, B. K. S., F. N. K. Yusufi, Mariatia, Y. Yang and D.-Y. Lee. 2013. Enhanced expression of codon optimized interferon gamma in CHO cells. J. Biotechnol., 167(3): 326-333.

Courtes, F. C., J. Lin, H. L. Lim, S. W Ng, N. S. C. Wong, G. Koh, L. Vardy, M. G. S. Yap, B. Loo and D.-Y. Lee. 2013. Translatome analysis of CHO cells to identify key growth genes. J. Biotechnol., 167(3): 215-224.

Lakshmanan, M., Z. Zhang, B. Mohanty, J.-Y. Kwon, H.-Y. Choi, H.-J. Nam, D.-I. Kim and D.-Y. Lee. 2013. Elucidating the rice cells metabolism under flooding and drought stresses using flux-based modelling and analysis. Plant Physiol., 162(4): 2140-2150.

Chung, B. K. S., T. Dick and D.-Y. Lee. 2013. In silico analyses for the discovery of tuberculosis drug targets. J. Antimicrob. Chemoth., 68(12): 2701-2709.

Lee, T. S., Y. S. Ho, H. C. Yeo, J. P. Y. Lin and D.-Y. Lee. 2013. Precursor mass prediction by clustering ionization products in LC-MS-based metabolomics. Metabolomics, 9(6): 1301-1310.

Chung, B. K. S., M. Lakshmanan, M. Klement, C. B. Ching and D.-Y. Lee. 2013. Metabolic reconstruction and flux analysis in Pichia yeasts. Appl. Microbiol. Biotechnol., 97(5): 1865-1873. [Invited Min-Review]

Chung, B. K. S., M. Lakshmanan, M. Klement, B. Mohanty and D.-Y. Lee. 2013. Genome-scale in silico modeling and analysis for designing synthetic terpenoid-producing microbial cell factories. Chem. Eng. Sci., 103: 100-108. [Special Issue: Synthetic Biology, invited]

Kwok, J. J. M., N. Yu, I. A. Karimi and D.-Y. Lee. 2013. Microgrid scheduling for reliable, cost effective and environmentally friendly management. Ind. Eng. Chem. Res., 52(1): 142-151.

Chung, B. K. S. and D.-Y. Lee. 2012. Computational codon optimization of synthetic gene for protein expression. BMC Syst. Biol., 6: 134. [Highly accessed].

Mohanty, B., V. Hearth, E. Wijaya, H. C. Yeo, B. G. de los Reyes and D.-Y. Lee. 2012. Patterns of cis-element enrichment reveal potential regulatory modules involved in the transcriptional regulation of anoxia response of japonica rice. Gene, 511(2): 235-242.

Kim, Y. J., H.-J. Eom, E.-Y. Seo, D.-Y. Lee, J. H. Kim and N. S. Han. 2012. Development of a chemically defined minimal medium for the exponential growth of Leuconostoc mesenteroides ATCC8293. J. Microbial. Biotechnol., 22(11): 1518-1522.

Aggarwal, S., I. A. Karimi, J. J. Kilbane II and D.-Y. Lee. 2012. Roles of sulfite oxidoreductase and fulfite reductase in improving desulfurization by Rhodococcus erythropolis. Mol. BioSyst., 8(10): 2724-2732.

Chong, W. P. K., S. H. Thng, A. P. Hui, D.-Y. Lee, E. C. Y. Chan and Y. S. Ho. 2012. LC-MS-based metabolic characterization of high monoclonal antibody-producing Chinese hamster ovary cells. Biotechnol. Bioeng., 109(12): 3103-3111.

Selvarasu, S., Y. S. Ho, W. P. K. Chong, N. S. C. Wong, F. N. K. Yusufi, Y. Y. Lee, M. G. S. Yap and D.-Y. Lee. 2012. Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture. Biotechnol. Bioeng., 109(6): 1415-1429. [Special Issue: CHO Cell Genomics, invited] [Highlighted as Top 25 most accessed article from Jan-Dec 2012]

Wu, S. M., K. S. Tan, H. Chen, T. T. Beh, H. C. Yeo, S. K.-L. Ng, S. Wei, D.-Y. Lee, A. B.-H. Choo and K. K.-K. Chan. 2012. Enhanced production of neuroprogenitors, dopaminergic neurons and identification of target genes by overexpression of Sonic hedgehog in human embryonic stem cells. Stem Cells Dev., 21(5): 729-741.

Kang, J.-S., T.-Y. Lee and D.-Y. Lee. 2012. Robust optimization for engineering design. Eng. Optimiz., 44(2): 175-194.

Yeo, H. C., T. T. Beh, J. Q. J. Ling, K. K.-K. Chan and D.-Y. Lee. 2011. Integrated transcriptome and in silico binding sites analysis reveals E2Fs as global coordinator of self-renewal in human pluripotent stems cells. PLoS ONE, 6(11): e27231.

Koh, G., A. Low, D. Poh, S. K. Ng, V. V. T. Wong, V. Vagenende, K.-P. Lam and D.-Y. Lee. 2011. Integrative analysis workflow for the structural and functional classification of C-type lectins. BMC Bioinformatics, 12(Suppl 14): S5.

Aggarwal, S., I. A. Karimi and D.-Y. Lee. 2011. Reconstruction of a genome-scale metabolic network of Rhodococcus erythropolis for desulfurization studies. Mol. BioSyst., 7(11): 3122-3131.

Ahn, J., B. K. S. Chung, D.-Y. Lee, M. Park, I. A. Karimi, J.-K. Jung and H. Lee. 2011. NADPH-dependent pgi-gene knockout Escherichia coli metabolism producing shikimate on different carbon sources. FEMS Microbiol. Lett., 324(1): 10-16.

Naraharisetti, P. K., I. A. Karimi, A. Anand and D.-Y. Lee. 2011. A linear diversity constraint – application to scheduling in microgrids. Energy, 36: 4235-4234.

Koh, G. and D.-Y. Lee. 2011. Mathematical modeling and sensitivity analysis of the integrated TNFa-mediated apoptotic pathway for identifying key regulators. Comput. Biol. Med., 41: 512-528.

Ding, V. M. Y., P. J. Boersema, L. Y. Foong, C. Preisinger, G. Koh, S. Natarajan, D.-Y. Lee, J. Boekhorst, B. Snel, S. Lemeer, A. J. R. Heck and A. Choo. 2011. Tyrosine phosphorylation profiling in FGF-2 stimulated human embryonic stem cells. PLoS ONE, 6(3): e17538.

Chong, W. P. K., F. N. K. Yusufi, D.-Y. Lee, S. G. Reddy, N. S. C. Wong, C. K. Heng, M. G. S. Yap and Y. S. Ho. 2011. Metabolomics-based identification of apoptosis-inducing metabolites in fed-batch CHO culture media. J. Biotechnol., 151: 218-224.

Aggarwal, S., I. A. Karimi and D.-Y. Lee. 2011. Flux-based analysis of sulfur metabolism in desulfurizing strains of Rhodococcus erythropolis. FEMS Microbiol. Lett., 315: 115-121.

Widiastuti, H., J. Y. Kim, S. Selvarasu, I. A. Karimi, H. Kim, J.-S. Seo and D.-Y. Lee. 2011. Genome-scale modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis. Biotechnol. Bioeng., 108: 655-665.

Lee, D.-Y., B. K. S. Chung, F. N. K. Yusufi and S. Selvarasu. 2011. In silico genome-scale modeling and analysis for identifying anti-tubercular drug targets. Drug Develop. Res., 72(2): 121-129. [Special Issue: In Silico Tools in Drug Design, invited]

Selvarasu, S., D. Y. Kim, I. A. Karimi and D.-Y. Lee. 2010. Combined data preprocessing and multivariate statistical analysis characterizes fed-batch culture of mouse hybridoma cells for rational medium design, J. Biotechnol., 150: 94-100.

Chung, B. K. S., S. Selvarasu, C. Andrea, J. Ryu, H. Lee, J. Ahn, H. Lee and D.-Y. Lee. 2010. Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement. Microb. Cell Fact., 9: 50. [Highly accessed].

Chong, W. P. K., S. G. Reddy, F. N. K. Yusufi, D.-Y. Lee, N. S. C. Wong, C. K. Heng, M. G. S. Yap and Y. S. Ho. 2010. Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: overexpression of malate dehydrogenase II. J. Biotechnol., 147: 116-121.

Lee, F. C., Rangaiah, G. P. and D.-Y. Lee. (2010) Modeling and optimization of a multi-product biosynthesis factory for multiple objectives. Metab. Eng., 12: 251-267.

Chin, J., Koh, G. and D.-Y. Lee (2010) How necessary is a fast testkit for mitigation of pandemic flu? J. R. Soc. Interface, 7: 1033-1047.

Selvarasu, S., Karimi, I. A., Ghim, G.-H. and D.-Y. Lee. (2010) Genome-scale modeling and in silico analysis of mouse cell metabolic network. Mol. Biosyst., 6: 152-161. [Cover paper][Highly accessed].

Chung, B. K. S. and D.-Y. Lee. (2009) Flux-sum analysis: a metabolite-centric approach for understanding the metabolic network. BMC Syst. Biol., 3: 117.

Chong, W. P. K., Goh, L. T., Reddy, S. G., Yusufi, F. N. K., Lee, D.-Y., Wong, N. S. C., Heng, C. K., Yap, M. G. S. and Ho, Y. S. (2009) Metabolomics profiling of extracellular metabolites in recombinant Chinese hamster ovary fed-batch culture. Rapid Commun. Mass Sp., 23: 3763-3771.

Kim, P.-J., Lee, D.-Y. and Jeong, H. (2009) Centralized modularity of N-linked glycosylation pathways in mammalian cells. PLoS ONE, 4(10): e7317.

Kharkwal, S., Karimi, I. A., Chang, M. W. and Lee, D.-Y. (2009) Strain improvement and process development for biobutanol production. Recent Pat. Biotechnol., 3: 202-210.

Jung, T.-S., Yeo, H. C., Reddy, S. G., Cho, W.-S. and Lee, D.-Y. (2009) WEbcoli: an interactive and asynchronous web application for in silico design and analysis of genome-scale E. coli model. Bioinformatics, 25(21): 2850-2852.

Ow, D. S. W., Lee, D.-Y., Tung, H. H. and Chao, S. L. (2009) Plasmid regulation and systems-level effects on Escherichia coli metabolism. In S. Y. Lee (ed), Systems Biology and Biotechnology of Escherichia coli. Springer, Germany, pp. 273-294.

Oh, Y.-G., Lee, D.-Y., Lee, S. Y. and Park, S. (2009). Multiobjective flux balancing using the NISE method for metabolic network analysis. Biotechnol. Prog., 25(4): 999-1008.

Selvarasu, S., Wong, V. V. T., Karimi, I. A. and Lee, D.-Y. (2009) Elucidation of metabolism in hybridoma cells grown in fed-batch culture by genome-scale modeling. Biotechnol. Bioeng., 102(5): 1494-1504.

Selvarasu, S., Ow, D. S.-W., Lee, S. Y., Lee, M. M., Oh, S. K.-W., Karimi, I. A. and Lee, D.-Y. (2009) Characterizing Escherichia coli DH5α growth and metabolism in a complex medium using genome-scale flux analysis. Biotechnol. Bioeng., 102(3): 923-934.

Lee, D.-Y., Saha, R., Yusufi, F. N. K., Park, W. and Karimi, I. A. (2009) Web-based applications for building, managing and analyzing kinetic models of biological systems. Brief. Bioinform., 10: 65-74.

Yusufi F.N.K., Park W., Lee M.M., Lee D.-Y. (2009) An alpha-numeric code for representing N-linked glycan structures in secreted glycoproteins. Bioproc. Biosys. Eng., 32: 97-107.

Ow, D. S.-W.,Lee, D.-Y., Yap, M. G-S. and Oh, S. K.-W. (2009) Identification of cellular objective for elucidating the physiological state of plasmid-bearing Escherichia coli using genome-scale in silico analysis. Biotechnol. Prog., 25(1): 61-67.

Lee, F. C., Rangaiah, G. P. and Lee, D.-Y. (2008) Optimization of a multi-product microbial cell factory for multiple objectives-a paradigm for metabolic pathway recipe. In G. P. Rangaiah (ed), Multi-objective Optimization: Techniques and Applications in Chemical Engineering. World Scientific, Singapore.

Ahn, J. O., Lee, H. W., Saha, R., Park, M. S., Jung, J.-K. and Lee, D.-Y. (2008) Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions. J. Microbiol. Biotechnol., 18(11): 1773-1784.

Kim, P.-J.*, Lee, D.-Y.*, Kim, T. Y., Jeong, H., Lee, S. Y. and Park, S. (2007) Metabolite-essentiality elucidates robustness of Escherichia coli metabolism. Proc. Natl. Acad. Sci. USA, 104(34): 13638-13642. (*Equally contributed authors)

Selvarasu, S., Lee, D.-Y. and Karimi, I. A. (2007) Identifying synergistically switching pathways for multi-product strain improvement using multiobjective flux balance analysis. Computer-Aided Chemical Engineering, 24: 1007-1012.

Choi, H. S., Kim, T. Y., Lee, D.-Y. and Lee, S. Y. (2007) Incorporating metabolic flux ratios into constraint-based flux analysis by using artificial metabolites and converging ratio determinants. J. Biotechnol., 129: 696-705.

Lee, D.-Y., Yun, C., Cho, A., Hou, B. K., Park, S. and Lee, S. Y. (2006) WebCell: a web-based environment for kinetic modeling and dynamic simulation of cellular networks. Bioinformatics, 22: 1150-1151.

Lee, D.-Y., Zimmer, R., Lee, S. Y. and Park, S. (2006) Colored Petri net modeling and simulation of signal transduction pathways. Metab. Eng., 8: 112-122.

Fan, L. T., Shafie, S., Bertók, B., Friedler, F., Lee, D.-Y., Seo, H., Park, S. and Lee, S. Y. (2005) Graph-theoretic approach for identifying catalytic or metabolic pathways. J. Chin. Inst. Eng., 28: 1021-1037.

Lee, S. J.*, Lee, D.-Y.*, Kim, T. Y., Kim, B. H. and Lee, S. Y. (2005) Metabolic engineering of Escherichia coli for the enhanced production of succinic acid based on genome comparison and in silico gene knock-out simulation. Appl. Environ. Microbiol., 71: 7880-7887. (*Equally contributed authors)

Lee, S. Y., Woo, H. M., Lee, D.-Y., Choi, H. S., Kim, T. Y. and Yun, H. (2005) Systems-level analysis of genome-scale in silico metabolic models using MetaFluxNet. Biotechnol. Bioproc. Eng., 10: 425-431.

Yun, H., Lee, D.-Y., Jeong, J., Lee, S. and Lee, S. Y. (2005) MFAML: a standard data structure for representing and exchanging metabolic flux models. Bioinformatics, 21: 3329-3330.

Lee, S. Y., Lee, D.-Y. and Kim, T. Y. (2005) Systems biotechnology for strain improvement. Trends Biotechnol., 23: 349-358.

Lee, D.-Y., Fan, L. T., Park, S., Lee, S. Y., Shafie, S., Bertók, B. and Friedler, F. (2005) Complementary identification of multiple flux distributions and multiple metabolic pathways. Metab. Eng., 7: 182-200.

Lee, D.-Y., Zimmer, R., Lee, S. Y., Hanisch, D. and Park, S. (2004) Knowledge representation model for systems-level analysis of signal transduction networks. Genome Informatics, 15(2): 234-243.

Hou, B. K., Kim, J. S., Jun, J. H., Lee, D.-Y., Kim, Y. W., Chae, S., Roh, M., In, Y.-H. and Lee, S. Y. (2004) BioSilico: an integrated metabolic database system. Bioinformatics, 20: 3270-3272.

Oh, Y.-G., Lee, D.-Y., Yun, H., Lee, S. Y. and Park, S. (2004) Multi-product trade-off analysis of E. coli by multiobjective flux balance analysis. Computer-Aided Chemical Engineering, 18: 1099-1104.

Lee, D.-Y., Sung, S. W., Lee, S. Y. and Park, S. 2004. Combined deterministic-stochastic approach for pharmacokinetic modeling. Ind. Eng. Chem. Res., 43: 1133-1143.

Lee, S. Y., Lee, D.-Y., Hong, S. H., Kim, T. Y., Yun, H., Oh, Y.-G. and Park, S. (2003) MetaFluxNet, a program package for metabolic pathway construction and analysis, and its use in large-scale metabolic flux analysis of Escherichia coli. Genome Informatics, 14: 23-33.

Lee, D.-Y., Yun, H., Park, S. and Lee, S. Y. (2003) MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis. Bioinformatics, 19: 2144-2146.

Lee, D.-Y., Lee, M., Lee, Y. and Park, S. (2003) Mp criterion-based multiloop PID controllers tuning for desired closed loop responses. Korean J. Chem. Eng., 20: 8-13.

Song, J., Park, H., Lee, D.-Y. and Park, S. (2002) Scheduling of actual size refinery processes considering environmental impacts with multiobjective optimization. Ind. Eng. Chem. Res., 41: 4794-4806.

Seo, H., Lee, D.-Y., Park, S., Fan, L. T., Shafie, S., Bertók, B. and Friedler, F. 2001. Graph-theoretical identification of pathways for biochemical reactions. Biotechnol. Lett., 23: 1551-1557.


Yusufi F. N. K., Jacob N. M., Mulukutla B. C., Kantardjieff A., Johnson K., Loo B. L. W., Chuah S. H., Nissom P. M., Yap M., Lee D.-Y., Hu W. S. Short-read sequencing reveals dynamic range of transcript abundance in CHO cells ESACT 2009, Dublin, Ireland

Yusufi F.N.K., Reddy S.G., Lee M.M., Lee D.-Y. (Mar 2008) GlycoVault: An online storage and visualization system for glycan structures. RECOMB 2008, Singapore

Yusufi F.N.K., Park W., Lee M.M., Lee D.-Y. (Dec 2007) GlycoDigit: An alpha-numeric representation system to visualize, store and compare glycan structure data. 18th International Conference on Genome Informatics, GIW, Singapore

Yusufi F.N.K., Wong N.S.C., Wong D.C.F., Yap M.G.S., Lee D.-Y. (Dec 2007) A multivariate approach to studying glycosylation gene expression in CHO cells. 18th International Conference on Genome Informatics, GIW, Singapore

Wong N.S.C., Wong D.C.F., Goh J.S.Y., Yusufi F.N.K., Lee D.-Y., Yap M.G.S. (July 2007) An intracellular analysis of the glycosylation process in CHO cells. Biochemical Engineering XIV, Harrison Hot Springs, BC, Canada